Dr. Sina Farzaneh, Ph.D.
Tissue Engineering & Scientific Director

Biomedical Scientist and Innovator in Tissue Engineering, Smart Biomaterials, and Regenerative Medicine

 

Dr. Sina Farzaneh is a multidisciplinary scientist and innovator with over 13 years of hands-on experience at the intersection of basic sciences, engineering, and medical research. With a robust academic and clinical research foundation, Dr. Farzaneh has consistently contributed to advancing the field of tissue engineering and regenerative medicine, bringing an engineering-informed lens to complex biological challenges.

Dr. Farzaneh earned his Ph.D. in Tissue Engineering and Regenerative Medicine from Shahid Beheshti University of Medical Sciences, where he merged his academic background in materials engineering with a passion for biomedicine. This unique blend enabled him to design and develop innovative smart biomaterials specifically tailored for tissue regeneration applications. His early research focused on integrating stem cells and their derivatives with responsive biomaterials to enhance healing in musculoskeletal injuries, chronic wounds, and skin regeneration.

In close collaboration with clinicians across craniofacial surgery, orthopedics, and dermatology, Dr. Farzaneh developed a critical understanding of the translational gap between laboratory innovation and bedside application. These interactions sharpened his focus on a fundamental challenge in regenerative medicine: the need for effective vasculogenesis and angiogenesis to support tissue repair and functional recovery.

Motivated to explore these mechanisms further, Dr. Farzaneh pursued postdoctoral research at the University of Massachusetts Amherst, beginning in 2021. There, he delved into the molecular biology of wound healing, with a focus on hemostasis, angiogenesis, cell migration, and the role of platelet activation in regenerative therapies. His work continues to influence new biomaterial designs that synchronize with the body’s natural healing cascades.

Dr. Farzaneh is a prolific researcher and published author, with over 11 peer-reviewed publications in tissue engineering, biomaterials, and drug delivery. He serves as a peer reviewer for journals such as Stem Cell Reviews and Reports and is an active member of the Tissue Engineering and Regenerative Medicine International Society (TERMIS). His leadership in research is characterized by a strong emphasis on scientific rigor, translational potential, and interdisciplinary collaboration.

Highlighted Research Contributions:

  1. Engineered implantable devices to study how material properties influence platelet activation and immune responses.

  2. Developed magnetically responsive hydrogels in combination with stem cells for bone tissue engineering.

  3. Created smart scaffolds designed to accelerate wound healing and promote vascularization.

  4. Designed anti-aging cosmetic formulations using a skin tissue engineering approach.

  5. Conducted pioneering work evaluating stem cell-seeded implants for spine surgery applications.

  6. Developed next-generation endovascular stents/grafts promoting anti-thrombotic endothelial behavior.

  7. Designed a magnetic substrate to modulate macrophage polarization for enhanced immune modulation.

  8. Developed molecularly imprinted polymer (MIP) nanoparticles for advanced drug delivery and biosensing.

  9. Built 3D silicone-based vascular models—including cerebral aneurysms and aortic vessels—for in-vitro studies in endothelialization, stenting, and injury simulation.

Dr. Farzaneh’s career continues to be defined by his commitment to creating functional, scalable solutions in regenerative medicine, with the goal of transforming experimental research into therapies that improve lives. He remains at the forefront of biomedical innovation, seamlessly integrating material science, biology, and clinical insight to address the future needs of medicine.

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